Escherichia coli, commonly abbreviated E. coli, is a Gramnegative, facultative anaerobic, rod-shaped bacterium commonly found in the lower intestine of warm-blooded organisms (endotherms). Most E. coli strains are harmless, but some serotypes can cause serious food poisoning in humans and are occasionally responsible for product recalls due to food contamination.

The versatility and sensitivity of the Hybrid Multispectral Analysis (HMA) methodology can be used to make measurements that would otherwise require complicated, time-consuming,  and error prone methods. There is no better example than the E. coli determination by HMA which uses a combination of fluorescence, scattering, and absorption.

The HMA method for E. coli, implemented through the LiquID station, consists of over 1000 individual optical readings. During each measurement cycle, readings are combined into a single value every 2 minutes using a proprietary algorithm. The large number of optical readings behind each E. coli determination adds statistical rigor, greater precision, and accuracy to every reported value.